Sunday, April 5, 2020

Making of Low Cost Ventilator

Chairman of the Mahindra Group, Anand Mahindra announced on Twitter that its specialised team at its Igatpuri and Mumbai plants have responded to the occasion and developed the first ventilator prototype in under 48 hours. "Anand Mahindra also tweeted that these medical ventilators developed by the team at Mahindra would cost under Rs 7,500, whereas other dedicated systems cost anywhere between Rs 5-10 lakh." This news was published on March 26, 2020. [1]
Yesterday's ToI carried an article where Dr Rajeev Chauhan, Assistant Professor at PGIMER said that the device claimed by Mahindra team was originally developed by PGIMER and IISc together from their one year effort and they have applied for ๐’‘๐’‚๐’•๐’†๐’๐’•. With the spread of the pandemic, they began talks with Mahindra group for large scale production. Dr Chauhan further said that representatives from the business house took details of his invention and 48 hours later introduced the ambu bag as their own product. Mahindra spokesperson denied this saying that they had in fact developed their product following ๐’๐’‘๐’†๐’ ๐’”๐’๐’–๐’“๐’„๐’† designs from a variety of sources. [2]
The BBC article, dated 1st April, titled, "Covid-19: The race to build coronavirus ventilators" starts with "The world needs more ventilators โ€“ but scaling up production is more complex than it seems. Around the world, thousands of volunteers are working hard to fill the gaps." The article continues, "In terms of their core function, ventilators are not extraordinarily complicated machines. Basically, they are sophisticated pumps ... So why are they so difficult to design? Because it isnโ€™t their function that is difficult. Itโ€™s that they have to operate in an extremely reliable way in a high-stakes environment." [3]
Of various ๐’๐’‘๐’†๐’ ๐’”๐’๐’–๐’“๐’„๐’† initiatives, the MIT News of March 26 shares an article titled, "MIT-based team works on rapid deployment of ๐’๐’‘๐’†๐’ ๐’”๐’๐’–๐’“๐’„๐’†, low-cost ventilator". ln this, "Clinical and design considerations will be published online; goal is to support rapid scale-up of device production to alleviate hospital shortages." The material cost is estimated to be USD 450 (~ Rs. 35000) instead of USD 30000 for standard ones. The article, continues, "The key to the simple, inexpensive ventilator alternative is a hand-operated plastic pouch called a bag-valve resuscitator, or Ambu bag. A tube is inserted into the patientโ€™s airway, as with a hospital ventilator, but then the pumping of air into the lungs is done by squeezing and releasing the flexible pouch. This is a task for skilled personnel, trained in how to evaluate the patient and adjust the timing and pressure of the pumping accordingly." [4]
MIT has come up with a dedicated website for this ๐’๐’‘๐’†๐’ ๐’”๐’๐’–๐’“๐’„๐’† project and is releasing information as and when it reaches a particular benchmark. The key ventilation specifications to be achieved by this low cost device is non-trivial. It is not just pumping a fixed volume at a fixed rate. Other than spec., hardware and software design details are being populated there (free registration). The download section as of now says, "๐–๐ž ๐ง๐จ๐ญ๐ž ๐ญ๐ก๐ž ๐ฎ๐ซ๐ ๐ž๐ง๐ญ ๐ข๐ง๐ญ๐ž๐ซ๐ž๐ฌ๐ญ ๐ข๐ง ๐จ๐ฎ๐ซ ๐œ๐จ๐๐ž ๐ฐ๐ก๐š๐ญ๐ž๐ฏ๐ž๐ซ ๐ฉ๐ซ๐จ๐ญ๐จ๐ญ๐ฒ๐ฉ๐ž ๐Ÿ๐จ๐ซ๐ฆ ๐ข๐ญ ๐ข๐ฌ ๐ข๐ง, ๐ก๐จ๐ฐ๐ž๐ฏ๐ž๐ซ, ๐ฌ๐จ๐ฆ๐ž ๐œ๐ซ๐ข๐ญ๐ข๐œ๐š๐ฅ ๐Ÿ๐ž๐š๐ญ๐ฎ๐ซ๐ž๐ฌ ๐š๐ซ๐ž ๐ง๐จ๐ง-๐Ÿ๐ฎ๐ง๐œ๐ญ๐ข๐จ๐ง๐š๐ฅ ๐š๐ง๐ ๐ญ๐ก๐ž๐ฌ๐ž ๐๐ž๐Ÿ๐ข๐œ๐ข๐ž๐ง๐œ๐ข๐ž๐ฌ ๐ฆ๐ฎ๐ฌ๐ญ ๐›๐ž ๐š๐๐๐ซ๐ž๐ฌ๐ฌ๐ž๐ ๐›๐ž๐Ÿ๐จ๐ซ๐ž ๐ฐ๐ž ๐Ÿ๐ž๐ž๐ฅ ๐ญ๐ก๐š๐ญ ๐ข๐ญ ๐ข๐ฌ ๐ฌ๐š๐Ÿ๐ž ๐ญ๐จ ๐ซ๐ž๐ฅ๐ž๐š๐ฌ๐ž. ๐–๐ก๐š๐ญ ๐ฐ๐ž ๐ฐ๐ข๐ฅ๐ฅ ๐ซ๐ž๐ฅ๐ž๐š๐ฌ๐ž ๐ฌ๐ก๐จ๐ซ๐ญ๐ฅ๐ฒ ๐ฌ๐ก๐จ๐ฎ๐ฅ๐ ๐จ๐ง๐ฅ๐ฒ ๐ฌ๐ž๐ซ๐ฏ๐ž ๐š๐ฌ ๐š ๐ซ๐ž๐Ÿ๐ž๐ซ๐ž๐ง๐œ๐ž ๐Ÿ๐จ๐ซ ๐ฒ๐จ๐ฎ๐ซ ๐๐ž๐ฏ๐ž๐ฅ๐จ๐ฉ๐ฆ๐ž๐ง๐ญ." Between March 20 and April 01, MIT team has conducted 4 testing; the first one was a comparative study on animal with their first version of the prototype against Medtronic's PB 840 ventilator system. [5]
Meanwhile, TechCrunch in its 31st March article titled, "Medtronic is sharing its portable ventilator design specifications and code for free to all" has Medtronic spokesperson saying, โ€œWe are sharing the design specifications for the [PB 560] to enable participants across industries to evaluate options for rapid ventilator manufacturing to help doctors and patients dealing with COVID-19.โ€ Itโ€™s worth noting that Medtronic ๐’Š๐’”๐’โ€™๐’• ๐’๐’‘๐’†๐’-๐’”๐’๐’–๐’“๐’„๐’Š๐’๐’ˆ the PB 560โ€™s design exactly: itโ€™s issuing a special โ€œ๐’‘๐’†๐’“๐’Ž๐’Š๐’”๐’”๐’Š๐’—๐’† ๐’๐’Š๐’„๐’†๐’๐’”๐’†โ€ specifically for the purposes of addressing this global coronavirus pandemic, and ๐ข๐ญ๐ฌ ๐ญ๐ž๐ซ๐ฆ ๐ž๐ง๐๐ฌ ๐ž๐ข๐ญ๐ก๐ž๐ซ ๐ฐ๐ก๐ž๐ง ๐ญ๐ก๐ž ๐–๐จ๐ซ๐ฅ๐ ๐‡๐ž๐š๐ฅ๐ญ๐ก ๐Ž๐ซ๐ ๐š๐ง๐ข๐ณ๐š๐ญ๐ข๐จ๐งโ€™๐ฌ ๐จ๐Ÿ๐Ÿ๐ข๐œ๐ข๐š๐ฅ ๐๐ฎ๐›๐ฅ๐ข๐œ ๐‡๐ž๐š๐ฅ๐ญ๐ก ๐„๐ฆ๐ž๐ซ๐ ๐ž๐ง๐œ๐ฒ ๐จ๐Ÿ ๐ˆ๐ง๐ญ๐ž๐ซ๐ง๐š๐ญ๐ข๐จ๐ง๐š๐ฅ ๐‚๐จ๐ง๐œ๐ž๐ซ๐ง (๐๐‡๐„๐ˆ๐‚) ๐ข๐ฌ ๐๐ž๐œ๐ฅ๐š๐ซ๐ž๐ ๐จ๐ฏ๐ž๐ซ, ๐จ๐ซ ๐จ๐ง ๐Ž๐œ๐ญ๐จ๐›๐ž๐ซ ๐Ÿ, ๐Ÿ๐ŸŽ๐Ÿ๐Ÿ’, ๐ฐ๐ก๐ข๐œ๐ก๐ž๐ฏ๐ž๐ซ ๐œ๐จ๐ฆ๐ž๐ฌ ๐Ÿ๐ข๐ซ๐ฌ๐ญ. [6]